What are mesenchymal stem cells (MSC)?
Mesenchymal stem cells, or MSCs, are multipotent stromal cells that can differentiate into a variety of cell types, including: osteoblasts (bone cells), chondrocytes (cartilage cells), myocytes (muscle cells) and adipocytes (fat cells).
What is Allograft tissue?
An allograft is tissue that is surgically transplanted or injected from one person to another.
Why are Human Cell & Tissue Products from Cord Tissue more effective?
Cord tissue mesenchymal stem cells have a faster doubling time than adult mesenchymal stem cells (because they are younger and contain a higher concentration of growth factors) The fitness of adult mesenchymal stem cells declines with age. Thus Cord tissue mesenchymal stem cells will have greater fitness than adult mesenchymal stem cells (as well as a different profile of growth factors)
How does MSC work?
The majority of the effects of MSCs is from trophic effects (exosomes/microvesicles releasing their 3000 growth factors), not from engraftment